Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50000008
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239134(CHEMBL4087516)
Affinity DataIC50: 2nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239146(CHEMBL4088988)
Affinity DataIC50: 10nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50134635(CHEMBL3746329 | US9637484, 3)
Affinity DataIC50: 33nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239130(CHEMBL4078376)
Affinity DataIC50: 50nMAssay Description:Inhibition of URAT1 (unknown origin) expressed in HEK293 cells assessed as reduction in [14C]uric acid uptake after 10 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239128(CHEMBL4059854 | US10266493, Example 2A | US1091985...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM290431(RDEA3170 | US10100016, Verinurad (RDEA3170) | CAS ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239129(CHEMBL4096685)
Affinity DataIC50: 80nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239131(CHEMBL4100597)
Affinity DataIC50: 83nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239143(CHEMBL4104410)
Affinity DataIC50: 127nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239137(CHEMBL4103898)
Affinity DataIC50: 203nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239147(CHEMBL4066146)
Affinity DataIC50: 215nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239136(CHEMBL4079640)
Affinity DataIC50: 241nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239151(CHEMBL4078667)
Affinity DataIC50: 261nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239133(CHEMBL4074756)
Affinity DataIC50: 390nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239150(CHEMBL4094280)
Affinity DataIC50: 597nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239145(CHEMBL4067774)
Affinity DataIC50: 713nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239144(CHEMBL4066753)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239141(CHEMBL4085591)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239142(CHEMBL4086514)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239148(CHEMBL4096139)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239152(CHEMBL4076833)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239132(CHEMBL4095219)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239138(CHEMBL4068847)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239139(CHEMBL4060192)
Affinity DataIC50: 9.84E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239140(CHEMBL4088415)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239149(CHEMBL4064028)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed