Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50000301
TargetAcetylcholinesterase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate measured after 8 mins in presence of BuChE inhibitor ethopropazine by Ellma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245716(CHEMBL4084610)
Affinity DataIC50: 2nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50433322(CHEMBL2376473)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition after 2 mins by DTN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245728(CHEMBL4063881)
Affinity DataIC50: 11nMAssay Description:Inhibition of equine serum BuChE using s-butyrylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured at 60 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245718(CHEMBL4095755)
Affinity DataIC50: 22nMAssay Description:Inhibition of human plasma AChE using acetyl-(beta-methyl)thiocholine as substrate pretreated for 30 mins followed by substrate addition after 25 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8970(N-[7-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)hepty...)
Affinity DataIC50: 35nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50433322(CHEMBL2376473)
Affinity DataIC50: 35nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition after 2 mins by DTNB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245717(CHEMBL4068410)
Affinity DataIC50: 50nMAssay Description:Inhibition of human RBC BuChE using s-butyrylthiocholine as substrate pretreated for 30 mins followed by substrate addition after 25 mins by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245727(CHEMBL4063321)
Affinity DataIC50: 55nMAssay Description:Inhibition of human BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM199199(N-(Pyridin-2-ylmethyl)-1,2,3,4-tetrahydroacridin-9...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured at 1 min i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245728(CHEMBL4063881)
Affinity DataIC50: 130nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate measured at 60 secs interval ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245715(CHEMBL4072478)
Affinity DataIC50: 150nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8970(N-[7-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)hepty...)
Affinity DataIC50: 340nMAssay Description:Inhibition of fetal bovine serum AChE using acetylthiocholine iodide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM10520(9-{[7-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)hept...)
Affinity DataIC50: 380nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245736(CHEMBL4099400)
Affinity DataIC50: 390nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245717(CHEMBL4068410)
Affinity DataIC50: 760nMAssay Description:Inhibition of human plasma AChE using acetyl-(beta-methyl)thiocholine as substrate pretreated for 30 mins followed by substrate addition after 25 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245716(CHEMBL4084610)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of fetal bovine serum AChE using acetylthiocholine iodide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245718(CHEMBL4095755)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human RBC BuChE using s-butyrylthiocholine as substrate pretreated for 30 mins followed by substrate addition after 25 mins by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245727(CHEMBL4063321)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245715(CHEMBL4072478)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine chloride as substrate after 5 mins by spectrophotometric metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245709(CHEMBL4082964)
Affinity DataIC50: 5.71E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 20 mins followed by substrate addition by DTNB reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM199199(N-(Pyridin-2-ylmethyl)-1,2,3,4-tetrahydroacridin-9...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245730(CHEMBL1730860)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM10520(9-{[7-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)hept...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fetal bovine serum AChE using acetylthiocholine iodide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245708(CHEMBL4067633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate measured at 12 secs interval for 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245729(CHEMBL4080162)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of human plasma BuChE using butyrylthiocholine iodine as substrate pretreated for 10 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245735(CHEMBL4079247)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of human plasma BuChE using butyrylthiocholine iodine as substrate pretreated for 10 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate measured at 12 secs interval for 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50245708(CHEMBL4067633)
Affinity DataIC50: 9.60E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured at 12 secs interval for 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured at 12 secs interval for 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed