Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50000485
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251343(CHEMBL4076580)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251343(CHEMBL4076580)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251344(CHEMBL4095035)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251349(CHEMBL4063583)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50117587(1-Benzyl-4-(5,6-dimethoxy-1-oxo-indan-2-ylidenemet...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50117587(1-Benzyl-4-(5,6-dimethoxy-1-oxo-indan-2-ylidenemet...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251344(CHEMBL4095035)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251347(CHEMBL4101018)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251349(CHEMBL4063583)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251345(CHEMBL4084842)
Affinity DataIC50: 4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251342(CHEMBL4073287)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251345(CHEMBL4084842)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251346(CHEMBL4082048)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251342(CHEMBL4073287)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251348(CHEMBL4099391)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251346(CHEMBL4082048)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251348(CHEMBL4099391)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251347(CHEMBL4101018)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251338(CHEMBL4076986)
Affinity DataIC50: 19nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251338(CHEMBL4076986)
Affinity DataIC50: 26nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 40nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251340(CHEMBL4070471)
Affinity DataIC50: 60nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251339(CHEMBL4083039)
Affinity DataIC50: 70nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251340(CHEMBL4070471)
Affinity DataIC50: 75nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251339(CHEMBL4083039)
Affinity DataIC50: 77nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of equine serum BuChE using s-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50251342(CHEMBL4073287)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of equine serum BuChE using s-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed