Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50000395
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50237727(CHEMBL4060938)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249034(CHEMBL4077729)
Affinity DataIC50: 2.42E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249036(CHEMBL4066742)
Affinity DataIC50: 3.38E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249039(CHEMBL4101998)
Affinity DataIC50: 4.24E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249038(CHEMBL1409841)
Affinity DataIC50: 4.54E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249041(CHEMBL4081253)
Affinity DataIC50: 4.96E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249040(CHEMBL4080320)
Affinity DataIC50: 5.95E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249037(CHEMBL4104553)
Affinity DataIC50: 6.41E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249035(CHEMBL4094266)
Affinity DataIC50: 6.75E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50249033(CHEMBL4078657)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced YO-PRO-1 Iodide uptake measured every 30 secs for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed