Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50001005
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM19187(CHEMBL396778 | (2S)-2-[({4-[(3-fluorophenyl)methox...)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50241461(Methylene Blue anhydrous | Methylenblau | bleu de ...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50029816(Ro-19-6327 | 5-Chloro-pyridine-2-carboxylic acid (...)
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50267489(CHEMBL4101770)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50110725(CHEMBL18116 | 5-(hydroxymethyl)-3-(3-methylphenyl)...)
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | benzoquinone | cid_4650 | CHEMB...)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM24781(2-phenylcyclohexa-2,5-diene-1,4-dione | Phenyl-p-b...)
Affinity DataIC50: 5.03E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50267488(CHEMBL4100724)
Affinity DataIC50: 5.37E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50267490(CHEMBL4091051)
Affinity DataIC50: 5.84E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM24781(2-phenylcyclohexa-2,5-diene-1,4-dione | Phenyl-p-b...)
Affinity DataIC50: 7.87E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | benzoquinone | cid_4650 | CHEMB...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50172756(N-benzyl-N-methylprop-2-yn-1-amine | Eutonyl | Ben...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50267489(CHEMBL4101770)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50267490(CHEMBL4091051)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50267488(CHEMBL4100724)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50359639(CHEMBL1928855)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human gastrointestinal mitochondria MAO-A using 1-methyl-4-(1-methylpyrrol-2-yl)-1,2,3,6-tetrahydropyridine as substrate after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50359639(CHEMBL1928855)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human liver mitochondria MAO-B using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as substrate after 15 mins by spectrophotometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | benzoquinone | cid_4650 | CHEMB...)
Affinity DataKi:  9.62E+3nMAssay Description:Competitive inhibition of human brain mitochondria MAO-A using kynuramine as substrate by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | benzoquinone | cid_4650 | CHEMB...)
Affinity DataKi:  2.03E+4nMAssay Description:Non-competitive inhibition of human brain mitochondria MAO-B using kynuramine as substrate by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2020
Entry Details Article
PubMed