Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50000555
LigandPNGBDBM50253249(CHEMBL4093351)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253250(CHEMBL4064039)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253243(CHEMBL4078681)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253248(CHEMBL4102957)
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253243(CHEMBL4078681)
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253249(CHEMBL4093351)
Affinity DataIC50: 32nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 43nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253250(CHEMBL4064039)
Affinity DataIC50: 76nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 87nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253249(CHEMBL4093351)
Affinity DataIC50: 200nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50: 280nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253250(CHEMBL4064039)
Affinity DataIC50: 550nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50: 900nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253248(CHEMBL4102957)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253243(CHEMBL4078681)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253253(CHEMBL4065083)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human PI4K2alpha (1 to 479 residues) by ADP Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human PI4KB (1 to 801 residues) by ADP Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253252(CHEMBL4086526)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetVacuolar protein sorting-associated protein 35(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of VPS35 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetPhosphoinositide 3-kinase regulatory subunit 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of VPS15 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253248(CHEMBL4102957)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of m-TOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human PIP5K2alpha (1 to 406 residues) by ADP Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed