Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50000228
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242849(CHEMBL4071757)
Affinity DataIC50: 798nMAssay Description:Inhibition of recombinant human HDAC1 using a fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 864nMAssay Description:Inhibition of recombinant human HDAC1 using a fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242819(CHEMBL4088425)
Affinity DataIC50: 903nMAssay Description:Inhibition of recombinant human HDAC1 using a fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242828(CHEMBL4096149)
Affinity DataIC50: 983nMAssay Description:Inhibition of recombinant human HDAC1 using a fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in Baculovirus insect cell expression system using [3H]-metabolically labeled acetylated histone subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242829(CHEMBL4085985)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in Baculovirus insect cell expression system using [3H]-metabolically labeled acetylated histone subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242819(CHEMBL4088425)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human ERG expressed in HEK293 cells after 9 mins by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242849(CHEMBL4071757)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of recombinant human ERG expressed in HEK293 cells after 9 mins by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human ERG expressed in HEK293 cells after 9 mins by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50242828(CHEMBL4096149)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of recombinant human ERG expressed in HEK293 cells after 9 mins by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed