Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50000569
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 86nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 740nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 820nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253910(CHEMBL4089719)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253885(CHEMBL4085339)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BRD4 bromodomain 1 (49 to 170 residues) expressed in Escherichia coli using biotinylated peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253909(CHEMBL4072185)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253886(CHEMBL4077583)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253910(CHEMBL4089719)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BRD4 bromodomain 1 (49 to 170 residues) expressed in Escherichia coli using biotinylated peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253885(CHEMBL4085339)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253886(CHEMBL4077583)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BRD4 bromodomain 1 (49 to 170 residues) expressed in Escherichia coli using biotinylated peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253908(CHEMBL4077397)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253887(CHEMBL4076445)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed