Compile Data Set for Download or QSAR
Report error Found 186 Enz. Inhib. hit(s) with all data for entry = 50002884
TargetGlycine receptor subunit alpha-3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464255(CHEMBL4083687)
Affinity DataKd:  70nMAssay Description:Binding affinity to human GlyRalpha3cryst by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464255(CHEMBL4083687)
Affinity DataEC50:  300nMAssay Description:Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464234(CHEMBL4284872)
Affinity DataKd:  300nMAssay Description:Binding affinity to human GlyRalpha3cryst by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464255(CHEMBL4083687)
Affinity DataEC50:  370nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464360(CHEMBL4282578)
Affinity DataEC50:  500nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1/beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464234(CHEMBL4284872)
Affinity DataEC50:  600nMAssay Description:Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464234(CHEMBL4284872)
Affinity DataEC50:  700nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464361(CHEMBL4290867)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464264(CHEMBL4295252)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464258(CHEMBL4285964)
Affinity DataEC50:  1.21E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464328(CHEMBL4278706)
Affinity DataEC50:  2.10E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464263(CHEMBL4277386)
Affinity DataEC50:  2.30E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464257(CHEMBL4290271)
Affinity DataEC50:  2.30E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464329(CHEMBL4281910)
Affinity DataEC50:  2.50E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464261(CHEMBL4292781)
Affinity DataEC50:  2.70E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464260(CHEMBL4282176)
Affinity DataEC50:  3.10E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464265(CHEMBL4292523)
Affinity DataEC50:  3.30E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464254(CHEMBL4276816)
Affinity DataEC50:  3.70E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464254(CHEMBL4276816)
Affinity DataEC50:  3.70E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464327(CHEMBL4290682)
Affinity DataEC50:  4.20E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464231(CHEMBL4283686)
Affinity DataEC50:  5.20E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464231(CHEMBL4283686)
Affinity DataEC50:  5.20E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464305(CHEMBL4291111)
Affinity DataEC50:  5.40E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464259(CHEMBL4290451)
Affinity DataEC50:  6.10E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464271(CHEMBL4279153)
Affinity DataEC50:  7.12E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464350(CHEMBL4280238)
Affinity DataEC50:  8.70E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464254(CHEMBL4276816)
Affinity DataEC50:  1.24E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464256(CHEMBL4294200)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464276(CHEMBL4283923)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464277(CHEMBL4286144)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464278(CHEMBL4278590)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464279(CHEMBL4285932)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464272(CHEMBL4282623)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464273(CHEMBL4277515)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464274(CHEMBL4284691)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464275(CHEMBL4292580)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464268(CHEMBL4279655)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464269(CHEMBL4283720)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464270(CHEMBL4294293)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464266(CHEMBL4282966)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464267(CHEMBL4288687)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464292(CHEMBL4279557)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464293(CHEMBL4282547)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464294(CHEMBL4285938)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464295(CHEMBL4293829)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464288(CHEMBL4283380)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464289(CHEMBL4278067)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464290(CHEMBL4279936)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464291(CHEMBL4278482)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464284(CHEMBL4291160)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
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