Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50001029
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50100436(CHEMBL412768 | NH2-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50100436(CHEMBL412768 | NH2-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267969(Sargahydroquinoic Acid)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267967(CHEMBL4064412)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267967(CHEMBL4064412)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267969(Sargahydroquinoic Acid)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267967(CHEMBL4064412)
Affinity DataIC50: 6.93E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataIC50: 9.73E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267969(Sargahydroquinoic Acid)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267969(Sargahydroquinoic Acid)
Affinity DataKi:  1.60E+3nMAssay Description:Mixed type inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267968(CHEMBL4085945)
Affinity DataKi:  2.90E+3nMAssay Description:Noncompetitive inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50267967(CHEMBL4064412)
Affinity DataKi:  4.00E+3nMAssay Description:Mixed type inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2020
Entry Details Article
PubMed