Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50002720
LigandPNGBDBM50462076(CHEMBL1091826)
Affinity DataEC50:  16nMAssay Description:Activation of caspase cascade in human T47D cells using N-(Ac-DEVD)-N'-ethoxycarbonyl-R110 fluorogenic substrate incubated for 48 hrs by fluorescent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369722(US10233160, Compound 12 | US9981925, Compound 12)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369712(US10233160, Compound 2 | US9981925, Compound 2)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369718(US10233160, Compound 8 | US9981925, Compound 8)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369720(US10233160, Compound 10 | US9981925, Compound 10)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369721(US10233160, Compound 11 | US9981925, Compound 11)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369725(US10233160, Compound 15 | US9981925, Compound 15)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369726(US10233160, Compound 16 | US9981925, Compound 16)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369728(US10233160, Compound 18 | US9981925, Compound 18)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369714(US10233160, Compound 4 | US9981925, Compound 4)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369724(US10233160, Compound 14 | US9981925, Compound 14)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369723(US10233160, Compound 13 | US9981925, Compound 13)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369727(US10233160, Compound 17 | US9981925, Compound 17)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369668(US10233160, Compound 1 | US9981925, Compound 1)
Affinity DataIC50: 101nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHeparanase(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50462074(CHEMBL4251007)
Affinity DataIC50: 350nMAssay Description:Inhibition of activation of recombinant human pro-heparanase expressed in CHO cells by dimethylmethylene blue based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369719(US10233160, Compound 9 | US9981925, Compound 9)
Affinity DataIC50: 501nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369716(US10233160, Compound 6 | US9981925, Compound 6)
Affinity DataIC50: 501nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369715(US10233160, Compound 5 | US9981925, Compound 5)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50462075(CHEMBL4239130)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM369713(US10233160, Compound 3 | US9981925, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant p70S6K T412E mutant (1 to 421 residues) in Sf21 insect cells using FITC-AHA-AKRRRLSSLRA-OH sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50462073(CHEMBL4241245)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHeparanase(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50462071(CHEMBL4240897)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of activation of recombinant human pro-heparanase expressed in CHO cells by dimethylmethylene blue based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50462077(CHEMBL4251297)
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50462072(CHEMBL4246256)
Affinity DataIC50: 5.21E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed