Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50001052
TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 4nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVYaminoluciferin as substrate pretreated for 2 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50268402(CHEMBL4101493)
Affinity DataIC50: 18nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVYaminoluciferin as substrate pretreated for 2 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate pretreated for 2 hrs followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 440nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells using Z-LRRaminoluciferin as substrate pretreated for 2 hrs followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50268402(CHEMBL4101493)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate pretreated for 2 hrs followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50268402(CHEMBL4101493)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells using Z-LRRaminoluciferin as substrate pretreated for 2 hrs followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed