Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50049311
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50332590(5-(5-fluoro-1H-indol-3-yl)pentan-1-amine | CHEMBL1...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238843(CHEMBL4068067)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50332589(4-(5-fluoro-1H-indol-3-yl)butan-1-amine | CHEMBL16...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50432565(CHEMBL2347181)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM217355(4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238832(CHEMBL4080413)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238837(GNF-Pf-3346 | CHEMBL581893)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50035203(CHEMBL3343353)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238837(GNF-Pf-3346 | CHEMBL581893)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238829(CHEMBL4098436)
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238830(CHEMBL4069712)
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238841(CHEMBL4098162)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238842(CHEMBL4090447)
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238831(CHEMBL251689)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238840(CHEMBL4089529)
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238835(CHEMBL4076541)
Affinity DataIC50: 756nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238831(CHEMBL251689)
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM93094(2-Guanidino-4-methylguinazoline)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50134036(cid_4044 | mefanamic acid | CHEMBL686 | CI-473 | C...)
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238825(CHEMBL4098081)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50134036(cid_4044 | mefanamic acid | CHEMBL686 | CI-473 | C...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM7462(cid_5280863 | CHEMBL150 | 3,5,7-trihydroxy-2-(4-hy...)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238837(GNF-Pf-3346 | CHEMBL581893)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238832(CHEMBL4080413)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238828(CHEMBL4072361)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50396177(NIFUROXAZIDE)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238826(CHEMBL1357558)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238833(CHEMBL1406871)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238836(CHEMBL4091272)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238841(CHEMBL4098162)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50077323(7-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 7...)
Affinity DataIC50: 5.79E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM81774(Sulpiride-S | CAS_15676-16-1 | Sulpiride-l | SULPI...)
Affinity DataIC50: 7.68E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238838(CHEMBL4092887)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238837(GNF-Pf-3346 | CHEMBL581893)
Affinity DataIC50: 9.31E+4nMAssay Description:Inhibition of MPO in human neutrophils assessed as reduction in HOCl production preincubated for 30 mins followed by H2O2 addition by APF staining ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50: 3.14E+5nMAssay Description:Inhibition of MPO in human neutrophils assessed as reduction in HOCl production preincubated for 30 mins followed by H2O2 addition by APF staining ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed