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Found
67
Enz. Inhib. hit(s) with all data for entry = 4870
Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81980
(CAS_87051-46-5 | NSC_65652 | Butanserin)
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Affinity Data
Ki: 0.450nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81814
(CAS_86487-64-1 | SETOPERONE | 5H-THIAZOLO[3,2A]PYR...)
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Affinity Data
Ki: 1nM
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Date in BDB:
12/26/2011
Entry Details
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82383
(NSC_26388 | CAS_26388 | Metopimazine)
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Affinity Data
Ki: 2.5nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82382
(CAS_72005 | NSC_72005 | R 50 970)
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Affinity Data
Ki: 2.5nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82382
(CAS_72005 | NSC_72005 | R 50 970)
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Affinity Data
Ki: 2.80nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
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Affinity Data
Ki: 3.5nM
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Date in BDB:
12/26/2011
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
Copy SMILES
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Affinity Data
Ki: 4nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50346422
(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
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Affinity Data
Ki: 4.10nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50024205
(CHEMBL18331 | 3-{2-[4-(4-Fluoro-benzoyl)-piperidin...)
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Affinity Data
Ki: 4.5nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
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Affinity Data
Ki: 5nM
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
Copy SMILES
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Affinity Data
Ki: 6.30nM
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Date in BDB:
12/26/2011
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
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Affinity Data
Ki: 7.10nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
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Affinity Data
Ki: 7.60nM
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
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Affinity Data
Ki: 7.90nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
Article
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82382
(CAS_72005 | NSC_72005 | R 50 970)
Copy SMILES
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Affinity Data
Ki: 7.90nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
Article
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50024205
(CHEMBL18331 | 3-{2-[4-(4-Fluoro-benzoyl)-piperidin...)
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Affinity Data
Ki: 7.90nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
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Affinity Data
Ki: 9.5nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Copy SMILES
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Affinity Data
Ki: 10nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82382
(CAS_72005 | NSC_72005 | R 50 970)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82382
(CAS_72005 | NSC_72005 | R 50 970)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81814
(CAS_86487-64-1 | SETOPERONE | 5H-THIAZOLO[3,2A]PYR...)
Copy SMILES
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Affinity Data
Ki: 10nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
Copy SMILES
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Affinity Data
Ki: 12nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50024205
(CHEMBL18331 | 3-{2-[4-(4-Fluoro-benzoyl)-piperidin...)
Copy SMILES
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Affinity Data
Ki: 18nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 18nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50024205
(CHEMBL18331 | 3-{2-[4-(4-Fluoro-benzoyl)-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50024205
(CHEMBL18331 | 3-{2-[4-(4-Fluoro-benzoyl)-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Copy SMILES
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Affinity Data
Ki: 22nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
Copy SMILES
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Affinity Data
Ki: 24nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50017720
(Piperoxan | CHEMBL31836 | PIPEROXAN1-(2,3-Dihydro-...)
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Affinity Data
Ki: 25nM
More data for this Ligand-Target Pair
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CHEMBL
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
Copy SMILES
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Affinity Data
Ki: 25nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM78576
(MLS000028463 | cid_941651 | SMR000058396 | CIS-THI...)
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Affinity Data
Ki: 25nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
Entry Details
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81814
(CAS_86487-64-1 | SETOPERONE | 5H-THIAZOLO[3,2A]PYR...)
Copy SMILES
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Affinity Data
Ki: 32nM
More data for this Ligand-Target Pair
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Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50017720
(Piperoxan | CHEMBL31836 | PIPEROXAN1-(2,3-Dihydro-...)
Copy SMILES
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Affinity Data
Ki: 42nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81814
(CAS_86487-64-1 | SETOPERONE | 5H-THIAZOLO[3,2A]PYR...)
Copy SMILES
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Affinity Data
Ki: 50nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81814
(CAS_86487-64-1 | SETOPERONE | 5H-THIAZOLO[3,2A]PYR...)
Copy SMILES
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Affinity Data
Ki: 52nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
Copy SMILES
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Affinity Data
Ki: 59nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/26/2011
Entry Details
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Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82383
(NSC_26388 | CAS_26388 | Metopimazine)
Copy SMILES
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Affinity Data
Ki: 60nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
12/26/2011
Entry Details
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Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81980
(CAS_87051-46-5 | NSC_65652 | Butanserin)
Copy SMILES
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Affinity Data
Ki: 60nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM81980
(CAS_87051-46-5 | NSC_65652 | Butanserin)
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Ki: 66nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM82383
(NSC_26388 | CAS_26388 | Metopimazine)
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Ki: 71nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50113332
(CHEMBL62919 | altanserin | 3-(2-(4-(4-fluorobenzoy...)
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Ki: 71nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50017720
(Piperoxan | CHEMBL31836 | PIPEROXAN1-(2,3-Dihydro-...)
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Ki: 79nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Ki: 120nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM55436
(Tolazoline | SMR000149600 | MLS000559484 | cid_604...)
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Ki: 120nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50346422
(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
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Ki: 160nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 200nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50113332
(CHEMBL62919 | altanserin | 3-(2-(4-(4-fluorobenzoy...)
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Affinity Data
Ki: 200nM
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Date in BDB:
12/26/2011
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50346422
(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
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Affinity Data
Ki: 220nM
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Date in BDB:
12/26/2011
Entry Details
Article
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PubMed
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Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50113332
(CHEMBL62919 | altanserin | 3-(2-(4-(4-fluorobenzoy...)
Copy SMILES
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Affinity Data
Ki: 280nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Alpha-2C adrenergic receptor
(Rat)
Janssen Pharmaceutica
Curated by
PDSP K
i
Database
Ligand
BDBM50113332
(CHEMBL62919 | altanserin | 3-(2-(4-(4-fluorobenzoy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 290nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
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In Depth
Date in BDB:
12/26/2011
Entry Details
Article
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