Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50001356
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277140(CHEMBL3244800)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277143(CHR 2797 | CHR-2797 | Tosedostat)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277159(CHEMBL4169814)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277156(CHEMBL4165328)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277140(CHEMBL3244800)
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277143(CHR 2797 | CHR-2797 | Tosedostat)
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277160(CHEMBL3244799)
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277160(CHEMBL3244799)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277156(CHEMBL4165328)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277157(CHEMBL4173240)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277142(CHEMBL4161892)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277141(CHEMBL4161496)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277142(CHEMBL4161892)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277158(CHEBI:17939 | 3123L | CL-13900 | GNF-Pf-2016 | P-6...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277158(CHEBI:17939 | 3123L | CL-13900 | GNF-Pf-2016 | P-6...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277150(CHEMBL4161744)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277157(CHEMBL4173240)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277159(CHEMBL4169814)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed