Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 23
TargetPeregrin(Human)
Oxford University

LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 114nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Oxford University

LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataIC50: 172nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Oxford University

LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 1(Human)
Oxford University

LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 619nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 1.01E+3nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetBromodomain-containing protein 1(Human)
Oxford University

LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetBromodomain-containing protein 1(Human)
Oxford University

LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataIC50: 3.52E+3nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Oxford University

LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Oxford University

LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Oxford University

LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetTranscription intermediary factor 1-alpha(Human)
Oxford University

LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetTranscription intermediary factor 1-alpha(Human)
Oxford University

LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetTranscription intermediary factor 1-alpha(Human)
Oxford University

LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed