Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50000837
TargetEstrogen receptor(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  2.30nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataEC50:  432nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261565(CHEMBL4098239)
Affinity DataIC50: 7nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261578(CHEMBL4085932)
Affinity DataIC50: 65nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261559(CHEMBL4067116)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataIC50: 110nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261577(CHEMBL4077445)
Affinity DataIC50: 120nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261563(CHEMBL4089618)
Affinity DataIC50: 129nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261562(CHEMBL4068479)
Affinity DataIC50: 198nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261581(CHEMBL4086863)
Affinity DataIC50: 202nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261575(CHEMBL4102621)
Affinity DataIC50: 210nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261580(CHEMBL4100191)
Affinity DataIC50: 232nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261583(CHEMBL4081744)
Affinity DataIC50: 250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261579(CHEMBL4064401)
Affinity DataIC50: 250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261570(CHEMBL4071193)
Affinity DataIC50: 250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261585(CHEMBL4073866)
Affinity DataIC50: 290nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261582(CHEMBL4083620)
Affinity DataIC50: 300nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 309nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261560(CHEMBL4094577)
Affinity DataIC50: 325nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261564(CHEMBL4059816)
Affinity DataIC50: 500nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261573(CHEMBL4098852)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261576(CHEMBL4078353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Evestra

Curated by ChEMBL
LigandPNGBDBM50261584(CHEMBL4062557)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed