Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50035648
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 1.60nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019947(CHEMBL299471 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019948(CHEMBL292006 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 3.30nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
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Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 4.20nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019946(CHEMBL56547 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 8.70nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 24nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Rat)
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Curated by ChEMBL
LigandPNGBDBM50019947(CHEMBL299471 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 29nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019948(CHEMBL292006 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 34nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 41nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
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Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019946(CHEMBL56547 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019954(CHEMBL57029 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-m...)
Affinity DataIC50: 55nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataIC50: 70nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019945(CHEMBL57140 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-m...)
Affinity DataIC50: 80nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM29644(APOMORPHINE HYDROCHLORIDE | SMR000059235 | APOMORP...)
Affinity DataIC50: 302nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
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Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 550nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019952(CHEMBL57306 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 598nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019954(CHEMBL57029 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-m...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019947(CHEMBL299471 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019948(CHEMBL292006 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019945(CHEMBL57140 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-m...)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 3.05E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019946(CHEMBL56547 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 3.22E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
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Curated by ChEMBL
LigandPNGBDBM50019953(CHEMBL59213 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-pip...)
Affinity DataIC50: 5.00E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019953(CHEMBL59213 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-pip...)
Affinity DataIC50: 5.50E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 5.69E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Rat)
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Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019954(CHEMBL57029 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019945(CHEMBL57140 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019952(CHEMBL57306 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed