Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50002329
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 50nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 160nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 190nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 210nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33857(SMR000287709 | cid_969825 | MLS000708242 | [5-amin...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 400nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33857(SMR000287709 | cid_969825 | MLS000708242 | [5-amin...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 490nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457205(CHEMBL4217303)
Affinity DataIC50: 600nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 600nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33601(MLS000115582 | SMR000092655 | cid_971668 | [5-amin...)
Affinity DataIC50: 680nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 750nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 810nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33857(SMR000287709 | cid_969825 | MLS000708242 | [5-amin...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33857(SMR000287709 | cid_969825 | MLS000708242 | [5-amin...)
Affinity DataIC50: 860nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 970nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33601(MLS000115582 | SMR000092655 | cid_971668 | [5-amin...)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457219(CHEMBL4212345)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33601(MLS000115582 | SMR000092655 | cid_971668 | [5-amin...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33601(MLS000115582 | SMR000092655 | cid_971668 | [5-amin...)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50326570((1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)m...)
Affinity DataIC50: 7.21E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457204(CHEMBL4212867)
Affinity DataIC50: 8.37E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457201(CHEMBL1288788)
Affinity DataIC50: 9.39E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457215(CHEMBL4203609)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457214(CHEMBL1290554)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM32806(cid_743706 | MLS000392028 | SMR000102548 | 1-benzo...)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457218(CHEMBL4212996)
Affinity DataIC50: 3.17E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457213(CHEMBL4217931)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457211(CHEMBL4205076)
Affinity DataIC50: 4.36E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457216(CHEMBL4211728)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457207(CHEMBL4215216)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457217(CHEMBL4210280)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50360399(CHEMBL1933870)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457208(CHEMBL4206846)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457209(CHEMBL4202629)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457210(CHEMBL1163357)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457212(CHEMBL4207366)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed