Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50002721
Target14-3-3 protein zeta/delta(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462079(CHEMBL4247970)
Affinity DataKd:  41nMAssay Description:Binding affinity to human full length 14-3-3zeta by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein zeta/delta(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462081(CHEMBL4243245)
Affinity DataKd:  370nMAssay Description:Binding affinity to recombinant human His-tagged 14-3-3zeta expressed in Escherichia coli K12 by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein zeta/delta(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462082(CHEMBL4245176)
Affinity DataKd:  1.14E+3nMAssay Description:Binding affinity to human full length 14-3-3zeta by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462078(CHEMBL4243744)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462080(CHEMBL4250552)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462083(CHEMBL4237531)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462084(CHEMBL4247540)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein sigma(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50462085(CHEMBL4240436)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TMR-GG-RLSHpSSLPG-NH2 binding to recombinant human GST-tagged 14-3-3-sigma preincubated for 30 mins followed by TMR-GG-RLSHpSSLPG-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target14-3-3 protein zeta/delta(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 9.30E+3nMAssay Description:Binding affinity to GST-tagged 14-3-3-zeta (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target14-3-3 protein gamma(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 1.64E+4nMAssay Description:Binding affinity to GST-tagged 14-3-3-gamma (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with PRAS4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed