Report error Found 360 Enz. Inhib. hit(s) with all data for entry = 50000434
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human BGT1/human GAT3 chimera C expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human BGT1/human GAT3 chimera C expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of human BGT1/human GAT3 chimera B expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of human BGT1/human GAT3 chimera B expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.39E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 4.07E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.13E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair


3D Structure (crystal)










