Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50000312
TargetProtein arginine N-methyltransferase 8(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PRMT8 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) incubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PRMT6 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243295(CHEMBL4084293)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 22nMAssay Description:Inhibition of PRMT3 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 63nMAssay Description:Inhibition of PRMT4 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245903(CHEMBL4073964)
Affinity DataIC50: 390nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245919(CHEMBL4097780)
Affinity DataIC50: 710nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245959(CHEMBL1617447)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245921(CHEMBL4087631)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245995(CHEMBL4078812)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245920(CHEMBL4079756)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245972(CHEMBL4077690)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245952(CHEMBL4095331)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245922(CHEMBL4067925)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245918(CHEMBL4091931)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245957(CHEMBL4101956)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245973(CHEMBL4075875)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245958(CHEMBL1625601)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT5 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245971(CHEMBL4060160)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245956(CHEMBL4103085)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50245994(CHEMBL4105514)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed