Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50001530
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283464(CHEMBL4162764)
Affinity DataIC50: 50nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)
Affinity DataIC50: 100nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)
Affinity DataIC50: 110nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)
Affinity DataIC50: 140nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283462(CHEMBL4176393)
Affinity DataIC50: 190nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283465(CHEMBL4168783)
Affinity DataIC50: 280nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283442(CHEMBL4172770)
Affinity DataIC50: 290nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283444(CHEMBL4173010)
Affinity DataIC50: 290nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283446(CHEMBL4169616)
Affinity DataIC50: 410nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283461(CHEMBL4164548)
Affinity DataIC50: 420nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283463(CHEMBL4176581)
Affinity DataIC50: 490nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283447(CHEMBL4168400)
Affinity DataIC50: 700nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283459(CHEMBL4159400)
Affinity DataIC50: 750nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283468(CHEMBL4165785)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283460(CHEMBL4177474)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283467(CHEMBL4162337)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283466(CHEMBL4176640)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed