Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50002021
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataIC50: 31.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50452329(CHEMBL4217221)
Affinity DataIC50: 53.2nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50452330(CHEMBL4214406)
Affinity DataIC50: 67nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50452331(CHEMBL4212727)
Affinity DataIC50: 82.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50452327(CHEMBL4217677)
Affinity DataIC50: 99.1nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 144nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Bovine)
Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50452328(CHEMBL4202604)
Affinity DataIC50: 164nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed