Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50002135
TargetCaspase-1(Human)
Edelris

Curated by ChEMBL
LigandPNGBDBM50453944(CHEMBL4217577)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant caspase1 expressed in Escherichia coli using AC-WEHD-AMC as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCaspase-1(Human)
Edelris

Curated by ChEMBL
LigandPNGBDBM50453945(CHEMBL4205880)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant caspase1 expressed in Escherichia coli using AC-WEHD-AMC as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCaspase-1(Human)
Edelris

Curated by ChEMBL
LigandPNGBDBM50453946(CHEMBL4205336)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant caspase1 expressed in Escherichia coli using AC-WEHD-AMC as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCaspase-1(Human)
Edelris

Curated by ChEMBL
LigandPNGBDBM50453946(CHEMBL4205336)
Affinity DataIC50: 86nMAssay Description:Inhibition of caspase1 in human THP1 cells assessed as LPS/ATP-induced IL-1beta release preincubated for 24 hrs in presence of LPS measured after ove...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed