Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50000473
TargetCytochrome P450 2C8(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 3.14E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed