Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50002042
TargetMacrophage metalloelastase(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM28476((2S)-2-({12-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452615(CHEMBL4217377)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452613(CHEMBL4207732)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452613(CHEMBL4207732)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM28476((2S)-2-({12-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452615(CHEMBL4217377)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452616(CHEMBL4218681)
Affinity DataIC50: 297nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452616(CHEMBL4218681)
Affinity DataIC50: 403nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452614(CHEMBL4214104)
Affinity DataIC50: 502nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452614(CHEMBL4214104)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed