Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50001560
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285411(CHEMBL4171400)
Affinity DataEC50:  335nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285403(CHEMBL4161979)
Affinity DataEC50:  301nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285404(CHEMBL4161587)
Affinity DataEC50:  130nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285405(CHEMBL4172198)
Affinity DataEC50:  395nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285406(CHEMBL4170248)
Affinity DataEC50:  370nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285407(CHEMBL4159626)
Affinity DataEC50:  457nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285391(CHEMBL4164934)
Affinity DataEC50:  38nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285408(CHEMBL4176218)
Affinity DataEC50:  1.95E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285409(CHEMBL4161107)
Affinity DataEC50:  431nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285410(CHEMBL4164519)
Affinity DataEC50:  678nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285398(CHEMBL4169906)
Affinity DataEC50:  95nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285401(CHEMBL4166140)
Affinity DataEC50:  92nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataEC50:  860nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285402(CHEMBL4173627)
Affinity DataEC50:  5.39E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285394(CHEMBL4168847)
Affinity DataEC50:  4.09E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataEC50:  79nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285412(CHEMBL4173333)
Affinity DataEC50:  208nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285413(CHEMBL4171709)
Affinity DataEC50:  396nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285404(CHEMBL4161587)
Affinity DataEC50:  1.81E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285414(CHEMBL4175624)
Affinity DataEC50:  429nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285397(CHEMBL4160788)
Affinity DataEC50:  194nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285389(CHEMBL4172842)
Affinity DataEC50:  88nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285390(CHEMBL4176765)
Affinity DataEC50:  46nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285391(CHEMBL4164934)
Affinity DataEC50:  4.93E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285392(CHEMBL4176991)
Affinity DataEC50:  151nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285389(CHEMBL4172842)
Affinity DataEC50:  1.26E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285393(CHEMBL4165713)
Affinity DataEC50:  211nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285394(CHEMBL4168847)
Affinity DataEC50:  65nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285395(CHEMBL4165004)
Affinity DataEC50:  204nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285396(CHEMBL4168361)
Affinity DataEC50:  2.25E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285388(CHEMBL4165421)
Affinity DataEC50:  175nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataEC50:  240nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285398(CHEMBL4169906)
Affinity DataEC50:  8.17E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285399(CHEMBL4176700)
Affinity DataEC50:  173nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285400(CHEMBL4175153)
Affinity DataEC50:  8.54E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285401(CHEMBL4166140)
Affinity DataEC50:  5.93E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285390(CHEMBL4176765)
Affinity DataEC50:  3.58E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataEC50:  2nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50285402(CHEMBL4173627)
Affinity DataEC50:  63nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed