Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50018704
TargetSodium channel protein type 9 subunit alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM217483(US9212182, 477 | US9212182, 478)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human Nav 1.7 channel expressed in HEK293 cells at -10 mV holding potential by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM217483(US9212182, 477 | US9212182, 478)
Affinity DataIC50: 907nMAssay Description:Inhibition of human Nav 1.7 channel expressed in HEK293 cells at -10 mV holding potential by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50079266(CHEMBL3416774)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to human V1a assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50079266(CHEMBL3416774)
Affinity DataKi:  13nMAssay Description:Binding affinity to human V1a assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50079269(CHEMBL3416767)
Affinity DataKi:  19nMAssay Description:Binding affinity to human V1a assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50611761(CHEMBL5286590)
Affinity DataKi:  273nMAssay Description:Binding affinity to human recombinant ALK L1196M mutant (1093 to 1411 residues) assessed as inhibition constant using 5'FAM-KKSRGDYMTMQIG-CONH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed