Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50001177
TargetTranscriptional enhancer factor TEF-1(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50271260(CHEMBL4130196)
Affinity DataKd:  15nMAssay Description:Binding affinity to human GST-tagged TEAD1 (194 to 411) expressed in Escherichia coli BL21(DE3) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2020
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50271260(CHEMBL4130196)
Affinity DataIC50: 25nMAssay Description:Inhibition of human His-tagged YAP (50 to 171 residues) interaction with human GST-tagged TEAD1 (194 to 411) expressed in Escherichia coli BL21(DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2020
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50271259(CHEMBL4129172)
Affinity DataIC50: 83nMAssay Description:Inhibition of Gal4-fused TEAD 1 (unknown origin) interaction with YAP expressed in human 293T cells by Dual-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2020
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM85507(NSC_4488 | CAS_4394-00-7 | Niflumic acid (Hit 16) ...)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to human His-tagged TEAD4 YBD (217 to 434 residues) expressed in Escherichia coli BL21(DE3) after 30 mins by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2020
Entry Details Article
PubMed