Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50000350
TargetCytochrome P450 3A4(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP3A4 (unknown origin) expressed in baculosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50247405(CHEMBL4077753)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]-IAAP from human P-gp expressed in high five insect cell membrane vesicles preincubated for 10 mins followed by photocrosslinki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50247406(CHEMBL4089061)
Affinity DataIC50: 760nMAssay Description:Displacement of [125I]-IAAP from human P-gp expressed in high five insect cell membrane vesicles preincubated for 10 mins followed by photocrosslinki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50247407(CHEMBL4076355)
Affinity DataIC50: 8.23E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed