Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50001640
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human DHFR assessed as reduction in consumption of NADPH using DHF as substrate by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs over 6 mins by spect...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human DHFR assessed as reduction in consumption of NADPH using DHF as substrate by fluorescence methodMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli assessed as reduction in consumption of NADPH using DHF as substrat...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli assessed as reduction in consumption of NADPH using DHF as substrat...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli assessed as reduction in consumption of NADPH using DHF as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 382nMAssay Description:Inhibition of human DHFR assessed as reduction in consumption of NADPH using DHF as substrate by fluorescence methodMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs over 6 mins by spect...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measure...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measure...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs over 6 mins by spect...More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs over 6 mins by spect...More data for this Ligand-Target Pair
Affinity DataIC50: 7.25E+4nMAssay Description:Inhibition of human DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measured for 2 mins by spectrophot...More data for this Ligand-Target Pair
Affinity DataIC50: 8.33E+4nMAssay Description:Inhibition of human DHFR assessed as reduction in consumption of NADPH using DHF as substrate incubated for 3 mins measured for 2 mins by spectrophot...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs ...More data for this Ligand-Target Pair
