Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50001650
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291300(CHEMBL4168752)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291298(CHEMBL4171877)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291293(CHEMBL4170837)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291296(CHEMBL4168522)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291299(CHEMBL4176617)
Affinity DataIC50: 250nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291327(CHEBI:68023 | Cudraflavone C)
Affinity DataIC50: 260nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291292(CHEMBL4167451)
Affinity DataIC50: 270nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
LigandPNGBDBM50291300(CHEMBL4168752)
Affinity DataIC50: 300nMAssay Description:Inhibition of human PDE1B2 catalytic domain (10 to 487 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50242015(CHEMBL518543 | Kuwanon C, 4 | kuwanon C)
Affinity DataIC50: 310nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291300(CHEMBL4168752)
Affinity DataIC50: 350nMAssay Description:Inhibition of human PDE9A2 catalytic domain (181 to 506 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291297(CHEMBL4164003)
Affinity DataIC50: 400nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291300(CHEMBL4168752)
Affinity DataIC50: 410nMAssay Description:Inhibition of human PDE5A1 catalytic domain (535 to 860 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291300(CHEMBL4168752)
Affinity DataIC50: 510nMAssay Description:Inhibition of human PDE10A2 catalytic domain (448 to 789 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291300(CHEMBL4168752)
Affinity DataIC50: 590nMAssay Description:Inhibition of human PDE2A3 catalytic domain (222 to 904 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50240972(8-prenylapigenin | 5,7-Dihydroxy-2-(4-hydroxy-phen...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291295(CHEMBL4160605)
Affinity DataIC50: 870nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291290(CHEMBL4173326)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291307(CHEMBL4174381)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291289(CHEMBL4162628)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291291(CHEMBL4168945)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291294(CHEMBL4160223)
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291303(CHEMBL4176273)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291305(CHEMBL4170952)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291306(CHEMBL4163032)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291302(CHEMBL4159517)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291304(CHEMBL4168408)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291301(CHEMBL4170139)
Affinity DataIC50: 9.21E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50291343(CHEMBL4169898)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed