Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 50002159
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >3.13E+3nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 57nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.24E+5nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 670nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 75nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 38nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 1.56E+3nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.06E+4nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >2.72E+4nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >2.72E+4nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 670nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.06E+4nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 1.58E+3nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >3.13E+3nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.24E+5nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.06E+4nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 290nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 1.82E+3nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >2.28E+5nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >1.24E+5nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 44nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >3.13E+3nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 88nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >8.36E+3nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 1.82E+3nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 1.19E+3nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 1.35E+3nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >770nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 73nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 2.36E+4nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: 1.18E+4nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina
Curated by ChEMBL
University of Messina
Curated by ChEMBL
Affinity DataEC50: >3.13E+3nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair



3D Structure (crystal)



