Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50001652
TargetGlycogen synthase kinase-3 alpha(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM8349(pyrazolo[3,4-b]pyridine analogue 4 | N-[5-bromo-6-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM8350(N-[5-chloro-6-(4-hydroxyphenyl)-1H-pyrazolo[3,4-b]...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291344(CHEMBL4165510)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant GSK3-beta (unknown origin) assessed as decrease in phosphorylation of CREB at serine-129 in presence of ATP[gamma-33P] by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291346(CHEMBL4162850)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant GSK3-beta (unknown origin) assessed as decrease in phosphorylation of CREB at serine-129 in presence of ATP[gamma-33P] by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291367(CHEMBL4164416)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant GSK3-beta (unknown origin) assessed as decrease in phosphorylation of CREB at serine-129 in presence of ATP[gamma-33P] by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291345(CHEMBL4169204)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant GSK3-beta (unknown origin) assessed as decrease in phosphorylation of CREB at serine-129 in presence of ATP[gamma-33P] by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291366(CHEMBL4172295)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant GSK3-beta (unknown origin) assessed as decrease in phosphorylation of CREB at serine-129 in presence of ATP[gamma-33P] by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291370(CHEMBL4172418)
Affinity DataIC50: 4nMAssay Description:Inhibition of human GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM8310(N-{5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl}cyclope...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM8579(N-[6-(pyridin-3-yl)furo[2,3-d]pyrimidin-4-yl]cyclo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291365(CHEMBL4161007)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant GSK3-beta (unknown origin) assessed as decrease in phosphorylation of CREB at serine-129 in presence of ATP[gamma-33P] by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50219330(CHEMBL303926)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human GSK3alpha using biotin-Ahx-AAAKRREILSRRP-S(PO3)YR-amide as substrate after 40 mins in presence of [33gammaP]-ATP by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50147458((3-{3-[4-(2-Methoxy-phenyl)-2,5-dioxo-2,5-dihydro-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50147463(3-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-4-[1-(...)
Affinity DataIC50: 26nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291369(CHEMBL4176856)
Affinity DataIC50: 280nMAssay Description:Inhibition of human GSK3beta using YRRAAVPPSPSLSRHSSPHQS(PO4)EDEEE-NH2 as substrate after 60 mins in presence of [33gammaP]-ATP by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Pig)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50291368(CHEMBL4167852)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of pig brain GSK3beta using GS1 as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2020
Entry Details Article
PubMed