Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50000616
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50414921(CHEMBL570812)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM60419(NAM | BDBM50295658)
Affinity DataIC50: 140nMAssay Description:Inhibition of MAGL from Wistar rat brain using 2-monooleoyl[1,2,3-H]glycerol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255239(CHEMBL4098069)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human MAGL expressed in African green monkey COS7 cells using 2-arachidonoyl-[3H]-glycerol as substrate after 20 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255237(CHEMBL4060693)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255236(CHEMBL4083351)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255281(CHEMBL4093753)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255240(CHEMBL4066972)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255279(CHEMBL4068325)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255280(CHEMBL4102429)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255272(CHEMBL4067643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255241(CHEMBL4079489)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255238(CHEMBL4071829)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255275(CHEMBL4086389)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255289(CHEMBL4084037)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human FAAH using AMC arachidonoylamide as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255282(CHEMBL4087366)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255287(CHEMBL4102813)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255242(CHEMBL4097523)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50128581(cyclohexyl biphenyl-3-ylcarbamate | CHEMBL77767 | ...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of MAGL from Wistar rat brain using 2-monooleoyl[1,2,3-H]glycerol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255288(CHEMBL4075839)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255273(CHEMBL4078532)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255274(CHEMBL4064925)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255276(CHEMBL4091802)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255278(CHEMBL4073675)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255277(CHEMBL4094290)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255243(CHEMBL4105223)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255271(CHEMBL4095055)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50255235(CHEMBL4078924)
Affinity DataKi:  412nMAssay Description:Competitive inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed