Compile Data Set for Download or QSAR
Report error Found 211 Enz. Inhib. hit(s) with all data for entry = 50001138
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270038(CHEMBL4062223)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Mouse)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270016(CHEMBL4070320)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at mouse CXCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Mouse)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at mouse CXCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270049(CHEMBL4096305)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270028(CHEMBL4071612)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270037(CHEMBL4070843)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Mouse)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270019(CHEMBL4065224)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at mouse CXCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270288(CHEMBL4062981)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270032(CHEMBL4092405)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270016(CHEMBL4070320)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270052(CHEMBL4080718)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270043(CHEMBL4090235)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270047(CHEMBL4075694)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270019(CHEMBL4065224)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270035(CHEMBL4076841)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270020(CHEMBL4090772)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270023(CHEMBL4073818)
Affinity DataIC50: 44nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270045(CHEMBL4081436)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270048(CHEMBL4078260)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270292(CHEMBL4084920)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270289(CHEMBL4074366)
Affinity DataIC50: 53nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270291(CHEMBL4068122)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270281(CHEMBL4081958)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270295(CHEMBL4099550)
Affinity DataIC50: 58nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270279(CHEMBL4083122)
Affinity DataIC50: 59nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270295(CHEMBL4099550)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270044(CHEMBL4089307)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270280(CHEMBL4098635)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270051(CHEMBL4104948)
Affinity DataIC50: 69nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270036(CHEMBL4065751)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270290(CHEMBL4097946)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270046(CHEMBL4059462)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270296(CHEMBL4094123)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270279(CHEMBL4083122)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270046(CHEMBL4059462)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270110(CHEMBL4089531)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443545(CHEMBL3091683)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270297(CHEMBL4066459)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270278(CHEMBL4072645)
Affinity DataIC50: 109nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270048(CHEMBL4078260)
Affinity DataIC50: 115nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270027(CHEMBL4105591)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270293(CHEMBL4086147)
Affinity DataIC50: 129nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270279(CHEMBL4083122)
Affinity DataIC50: 134nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270288(CHEMBL4062981)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270053(CHEMBL4088588)
Affinity DataIC50: 143nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270032(CHEMBL4092405)
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270033(CHEMBL4084652)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270286(CHEMBL4094400)
Affinity DataIC50: 168nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2020
Entry Details Article
PubMed
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