Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50012622
TargetSodium channel protein type 8 subunit alpha(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558815(CHEMBL4742035)
Affinity DataEC50:  6.20nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells assessed as decrease in peak current at pulses to 0 mV by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoKEGGSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558815(CHEMBL4742035)
Affinity DataEC50:  6.30nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells assessed as decrease in peak current at pulses to 0 mV by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoKEGGSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558815(CHEMBL4742035)
Affinity DataEC50:  72nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells incubated for 30 mins by FLIPRTetra fluorescent membrane potential assayMore data for this Ligand-Target Pair
Ligand InfoKEGGSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558815(CHEMBL4742035)
Affinity DataEC50:  72nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells incubated for 30 mins by FLIPRTetra fluorescent membrane potential assayMore data for this Ligand-Target Pair
Ligand InfoKEGGSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558815(CHEMBL4742035)
Affinity DataEC50:  72.4nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells incubated for 30 mins by FLIPRTetra fluorescent membrane potential assayMore data for this Ligand-Target Pair
Ligand InfoKEGGSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558815(CHEMBL4742035)
Affinity DataEC50:  72.4nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells incubated for 30 mins by FLIPRTetra fluorescent membrane potential assayMore data for this Ligand-Target Pair
Ligand InfoKEGGSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed