Compile Data Set for Download or QSAR
Report error Found 267 Enz. Inhib. hit(s) with all data for entry = 50000617
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  110nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255396(CHEMBL4067923)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255292(CHEMBL4061423)
Affinity DataEC50:  160nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255292(CHEMBL4061423)
Affinity DataEC50:  190nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  200nMAssay Description:Agonist activity at mGlu4 in C57/Bl6 mouse GP neurons assessed as inhibition of striatopallidal GABAergic inhibitory postsynaptic current amplitude b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255396(CHEMBL4067923)
Affinity DataEC50:  300nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255437(CHEMBL4085750)
Affinity DataEC50:  320nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255292(CHEMBL4061423)
Affinity DataEC50:  320nMAssay Description:Agonist activity at mGlu4 assessed as decrease in PF-induced presynaptic calcium amplitude in rat coronal slices by Fluo-4FF-AM dye based fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255337(CHEMBL4063142)
Affinity DataEC50:  380nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255292(CHEMBL4061423)
Affinity DataEC50:  380nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255406(CHEMBL4088782)
Affinity DataEC50:  380nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255415(CHEMBL4078629)
Affinity DataEC50:  400nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255336(CHEMBL4064187)
Affinity DataEC50:  420nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255390(CHEMBL4091029)
Affinity DataEC50:  440nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255337(CHEMBL4063142)
Affinity DataEC50:  440nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255397(CHEMBL4090179)
Affinity DataEC50:  490nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255406(CHEMBL4088782)
Affinity DataEC50:  490nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255340(CHEMBL4072316)
Affinity DataEC50:  500nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255292(CHEMBL4061423)
Affinity DataEC50:  510nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255406(CHEMBL4088782)
Affinity DataEC50:  530nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255388(CHEMBL4093492)
Affinity DataEC50:  540nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255450(CHEMBL4072409)
Affinity DataEC50:  540nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255390(CHEMBL4091029)
Affinity DataEC50:  600nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255388(CHEMBL4093492)
Affinity DataEC50:  600nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255406(CHEMBL4088782)
Affinity DataEC50:  640nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255390(CHEMBL4091029)
Affinity DataEC50:  660nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255347(CHEMBL4081842)
Affinity DataEC50:  720nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255435(CHEMBL4101970)
Affinity DataEC50:  760nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255336(CHEMBL4064187)
Affinity DataEC50:  800nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255454(CHEMBL4075877)
Affinity DataEC50:  800nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255439(CHEMBL4101745)
Affinity DataEC50:  900nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  900nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255415(CHEMBL4078629)
Affinity DataEC50:  980nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255389(CHEMBL4072781)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255336(CHEMBL4064187)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255407(CHEMBL4077705)
Affinity DataEC50:  1.07E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255347(CHEMBL4081842)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255388(CHEMBL4093492)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255389(CHEMBL4072781)
Affinity DataEC50:  1.25E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255390(CHEMBL4091029)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255437(CHEMBL4085750)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255441(CHEMBL4098424)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255339(CHEMBL4060360)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
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