Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50002217
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455197(CHEMBL4211533)
Affinity DataIC50: 36nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455199(CHEMBL4208299)
Affinity DataIC50: 41nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455204(CHEMBL4215559)
Affinity DataIC50: 52nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455215(CHEMBL4206243)
Affinity DataIC50: 56nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455213(CHEMBL4213223)
Affinity DataIC50: 83nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455201(CHEMBL4207712)
Affinity DataIC50: 92nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455203(CHEMBL4210603)
Affinity DataIC50: 92nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455211(CHEMBL4203364)
Affinity DataIC50: 93nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455216(CHEMBL4205202)
Affinity DataIC50: 95nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455187(CHEMBL4205707)
Affinity DataIC50: 169nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455214(CHEMBL4215028)
Affinity DataIC50: 212nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455208(CHEMBL4206210)
Affinity DataIC50: 265nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455186(CHEMBL4202837)
Affinity DataIC50: 283nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455218(CHEMBL4210567)
Affinity DataIC50: 285nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455207(CHEMBL4215960)
Affinity DataIC50: 294nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455209(CHEMBL4217927)
Affinity DataIC50: 337nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455217(CHEMBL4210999)
Affinity DataIC50: 361nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455205(CHEMBL4218503)
Affinity DataIC50: 561nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455196(CHEMBL4206761)
Affinity DataIC50: 598nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455212(CHEMBL4206649)
Affinity DataIC50: 622nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455202(CHEMBL4207170)
Affinity DataIC50: 797nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455200(CHEMBL4216684)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455210(CHEMBL4217111)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455195(CHEMBL4211716)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50455198(CHEMBL4205397)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human mPGES1 expressed in 293 cell microsomes preincubated for 15 mins followed by PGH2 substrate addition measured after 3 secs by enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed