Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50002583
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460160(CHEMBL4229131)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460148(CHEMBL4226053)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460159(CHEMBL4226281)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460149(CHEMBL4228477)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460147(CHEMBL4226031)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460146(CHEMBL4226546)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460158(CHEMBL4228366)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460150(CHEMBL4227376)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460154(CHEMBL4227238)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460143(CHEMBL4227642)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460159(CHEMBL4226281)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human SERT expressed in CHO cells assessed as reduction in [3H]5-HT uptake preincubated for 10 mins followed by [3H]5-HT addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460151(CHEMBL4228158)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460151(CHEMBL4228158)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460159(CHEMBL4226281)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460157(CHEMBL4228775)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460156(CHEMBL4228218)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460155(CHEMBL4225176)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460144(CHEMBL4228034)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460157(CHEMBL4228775)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460162(CHEMBL4229188)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460160(CHEMBL4229131)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50206765(CHEMBL3906576)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460152(CHEMBL4224788)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460143(CHEMBL4227642)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460148(CHEMBL4226053)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460142(CHEMBL4226603)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460151(CHEMBL4228158)
Affinity DataIC50: 16nMAssay Description:Inhibition of human SERT expressed in CHO cells assessed as reduction in [3H]5-HT uptake preincubated for 10 mins followed by [3H]5-HT addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460154(CHEMBL4227238)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460152(CHEMBL4224788)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460155(CHEMBL4225176)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460145(CHEMBL4225701)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50206765(CHEMBL3906576)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460162(CHEMBL4229188)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460146(CHEMBL4226546)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460147(CHEMBL4226031)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460156(CHEMBL4228218)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460157(CHEMBL4228775)
Affinity DataIC50: 45nMAssay Description:Inhibition of human SERT expressed in CHO cells assessed as reduction in [3H]5-HT uptake preincubated for 10 mins followed by [3H]5-HT addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460145(CHEMBL4225701)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460153(CHEMBL4225635)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460149(CHEMBL4228477)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460161(CHEMBL4228870)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460158(CHEMBL4228366)
Affinity DataKi:  111nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460150(CHEMBL4227376)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460153(CHEMBL4225635)
Affinity DataKi:  246nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460144(CHEMBL4228034)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460161(CHEMBL4228870)
Affinity DataKi:  468nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50460142(CHEMBL4226603)
Affinity DataKi:  546nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed