Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50001605
LigandPNGBDBM50287072(CHEMBL4159112 | US10759787, Example 12 | US1105981...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287050(CHEMBL4161265)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287052(CHEMBL4165937)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287284(CHEMBL4160111)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287068(CHEMBL4172576 | US10759787, Example 30 | US1105981...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287071(CHEMBL4164687 | US10759787, Example 29 | US1105981...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287125(CHEMBL4170327 | US10759787, Example 19 | US1105981...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287049(CHEMBL4162316)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287283(CHEMBL4177454)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287277(CHEMBL4170753 | US10759787, Example 18 | US1105981...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287048(CHEMBL4162499 | US10759787, Example 9 | US11059811...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287054(CHEMBL4174176)
Affinity DataIC50: 4nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287058(CHEMBL4169191)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287051(CHEMBL4169368)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287276(CHEMBL4162406)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287056(CHEMBL4169598 | US10759787, Example 20 | US1105981...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287306(CHEMBL4167587)
Affinity DataIC50: 6nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287119(CHEMBL4169762)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287053(CHEMBL4161444 | US10759787, Example 1 | US11059811...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287047(CHEMBL4176373)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287307(CHEMBL4176554 | US10759787, Example 6 | US11059811...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50287048(CHEMBL4162499 | US10759787, Example 9 | US11059811...)
Affinity DataIC50: 8nMAssay Description:Inhibition of EZH2 in human Pfeiffer cells assessed as reduction in H3K27 trimethylation after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50149895(CHEMBL3770000)
Affinity DataIC50: 20nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50287048(CHEMBL4162499 | US10759787, Example 9 | US11059811...)
Affinity DataIC50: 55nMAssay Description:Inhibition of EZH2 in human WSU-DLCL2 cells assessed as reduction in H3K27 trimethylation after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287055(CHEMBL4172992)
Affinity DataIC50: 331nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50287057(CHEMBL4165760)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2020
Entry Details Article
PubMed