Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 50002400
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataEC50:  8.80nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458139(CHEMBL4213336)
Affinity DataEC50:  268nMAssay Description:Agonist activity at human KOR expressed in HEK293 cell membranes assessed as stimulation of [35S]GTPgammaS binding after 30 mins by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458140(CHEMBL4210181)
Affinity DataEC50:  77nMAssay Description:Agonist activity at human KOR expressed in HEK293 cell membranes assessed as stimulation of [35S]GTPgammaS binding after 30 mins by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50083926((cyclazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethy...)
Affinity DataKi:  0.0520nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50007102(CHEMBL79470 | MR-2034 | 6,11-Dimethyl-3-(tetrahydr...)
Affinity DataKi:  0.0730nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50083926((cyclazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethy...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50007102(CHEMBL79470 | MR-2034 | 6,11-Dimethyl-3-(tetrahydr...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50018731(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458137(CHEMBL4210742)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]U69,593 from KOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50018731(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458147(CHEMBL4204891)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]U69,593 from KOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458145(CHEMBL4207341)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]U69,593 from KOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458137(CHEMBL4210742)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458144(CHEMBL4211113)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]U69,593 from KOR (unknown origin) expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458143(CHEMBL4215981)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458152(CHEMBL4207167)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50085020((3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hex...)
Affinity DataKi:  0.540nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50083926((cyclazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethy...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(EKC | CHEMBL55033 | 3-Cyclopropylmethyl-6-ethyl-8-...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(EKC | CHEMBL55033 | 3-Cyclopropylmethyl-6-ethyl-8-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458152(CHEMBL4207167)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50254563(3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(EKC | CHEMBL55033 | 3-Cyclopropylmethyl-6-ethyl-8-...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity to MOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(EKC | CHEMBL55033 | 3-Cyclopropylmethyl-6-ethyl-8-...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458141(CHEMBL4204304)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]DAMGO from MOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50085020((3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hex...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50018731(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458143(CHEMBL4215981)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50254563(3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50092176(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458142(CHEMBL4208635)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458148(CHEMBL4214248)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]U69,593 from KOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458146(CHEMBL4209962)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]U69,593 from KOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50092176(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458141(CHEMBL4204304)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458148(CHEMBL4214248)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]DAMGO from MOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50007102(CHEMBL79470 | MR-2034 | 6,11-Dimethyl-3-(tetrahydr...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(EKC | CHEMBL55033 | 3-Cyclopropylmethyl-6-ethyl-8-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to DOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(EKC | CHEMBL55033 | 3-Cyclopropylmethyl-6-ethyl-8-...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458147(CHEMBL4204891)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]naltrindole from DOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458140(CHEMBL4210181)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458146(CHEMBL4209962)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]DAMGO from MOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50085020((3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hex...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50458150(CHEMBL4208689)
Affinity DataKi:  5.30nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]naltrindole from DOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 79 total ) | Next | Last >>
Jump to: