Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50002617
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460552(CHEMBL4228659)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460567(CHEMBL4229132)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460557(CHEMBL4227727)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460565(CHEMBL4228359)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460554(CHEMBL4225382)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460563(CHEMBL4228147)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460562(CHEMBL4225583)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460556(CHEMBL4225110)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460555(CHEMBL4228716)
Affinity DataIC50: 1nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460566(CHEMBL4225114)
Affinity DataIC50: 2nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460559(CHEMBL4225422)
Affinity DataIC50: 3nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460551(CHEMBL4228878)
Affinity DataIC50: 3nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460566(CHEMBL4225114)
Affinity DataIC50: 3nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460553(CHEMBL4229187)
Affinity DataIC50: 3nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460558(CHEMBL4229206)
Affinity DataIC50: 3nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460564(CHEMBL4229242)
Affinity DataIC50: 3nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460552(CHEMBL4228659)
Affinity DataIC50: 4nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460567(CHEMBL4229132)
Affinity DataIC50: 5nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460560(CHEMBL4225871)
Affinity DataIC50: 5nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460554(CHEMBL4225382)
Affinity DataIC50: 5nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460551(CHEMBL4228878)
Affinity DataIC50: 6nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460561(CHEMBL4225440)
Affinity DataIC50: 10nMAssay Description:Inhibition of human kidney SGLT2 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460559(CHEMBL4225422)
Affinity DataIC50: 18nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460565(CHEMBL4228359)
Affinity DataIC50: 32nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460560(CHEMBL4225871)
Affinity DataIC50: 32nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460562(CHEMBL4225583)
Affinity DataIC50: 33nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460558(CHEMBL4229206)
Affinity DataIC50: 39nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460563(CHEMBL4228147)
Affinity DataIC50: 45nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460555(CHEMBL4228716)
Affinity DataIC50: 48nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460556(CHEMBL4225110)
Affinity DataIC50: 53nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460557(CHEMBL4227727)
Affinity DataIC50: 58nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460561(CHEMBL4225440)
Affinity DataIC50: 84nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460564(CHEMBL4229242)
Affinity DataIC50: 92nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50460553(CHEMBL4229187)
Affinity DataIC50: 206nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed