Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50002629
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
3D Structure (crystal)TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 1.21E+3nMAssay Description:Binding affinity to recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 4.78E+3nMAssay Description:Binding affinity to recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 7.01E+3nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 7.08E+3nMAssay Description:Binding affinity to recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 7.40E+3nMAssay Description:Binding affinity to recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 9.30E+3nMAssay Description:Binding affinity to recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 9.41E+3nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 3.37E+4nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair
