Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50002732
TargetPlatelet-derived growth factor receptor beta(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of recombinant human PDGFRbeta expressed in insect cells using Ulight-Poly GAT[EAY(1:1:1)]n as substrate after 30 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human KDR expressed in Sf9 insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 60 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human c-KIT using Ulight-TK peptide as substrate after 30 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human Flt4 using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human Src expressed in insect cells using Ulight-Poly GAT[EAY(1:1:1)]n as substrate after 10 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human CDK1/Cyclin B expressed in insect cells using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 15 mins by LANCE met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human Flt1 expressed in Sf9 insect cells using Ulight-TK peptide as substrate after 15 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human Aurora-A expressed in Sf21 insect cells using Ulight-RRRSLLE as substrate after 15 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human AKT1 expressed in insect cells using CREBtide as substrate after 60 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human FAK expressed in Sf9 insect cells using Ulight-TK peptide as substrate after 60 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human IGF1R using Ulight-TK peptide as substrate after 60 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human ABL expressed in insect cells using Ulight-TK peptide as substrate after 60 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human c-MET expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 60 mins by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataIC50: 950nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant human HER2 expressed in insect cells using biotinyl-betaAbetaAbetaAAEEEEYFELVAKKK as substrate after 30 mins by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462227(CHEMBL4249671)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462228(CHEMBL4249208)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462224(CHEMBL1488812)
Affinity DataIC50: 6.16E+3nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462229(CHEMBL4242953)
Affinity DataIC50: 6.47E+3nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462223(CHEMBL4238771)
Affinity DataIC50: 7.73E+3nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462223(CHEMBL4238771)
Affinity DataIC50: 9.38E+3nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462230(CHEMBL172517)
Affinity DataIC50: 9.61E+3nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human EGFR using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462223(CHEMBL4238771)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human RET V804L mutant using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462222(CHEMBL4241633)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of recombinant human EGFR using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462222(CHEMBL4241633)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462231(CHEMBL4238220)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM62811(MLS000114653 | 2-(4-methylphenyl)-3-oxidanyl-chrom...)
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462230(CHEMBL172517)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of recombinant human EGFR using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462221(CHEMBL4244888)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462221(CHEMBL4244888)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462223(CHEMBL4238771)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of recombinant human EGFR using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462226(CHEMBL1704021)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462224(CHEMBL1488812)
Affinity DataIC50: 5.16E+4nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462225(CHEMBL4237913)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462220(CHEMBL4239930)
Affinity DataIC50: 6.38E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462224(CHEMBL1488812)
Affinity DataIC50: 6.62E+4nMAssay Description:Inhibition of recombinant human RET V804L mutant using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462220(CHEMBL4239930)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462230(CHEMBL172517)
Affinity DataIC50: 6.84E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 7.81E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462226(CHEMBL1704021)
Affinity DataIC50: 8.26E+4nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50462225(CHEMBL4237913)
Affinity DataIC50: 9.27E+4nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed