Compile Data Set for Download or QSAR
Report error Found 151 Enz. Inhib. hit(s) with all data for entry = 50002433
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50088373(CHEBI:46295 | Vardenafil | cid_110634)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458485(CHEMBL4216635)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50458479(CHEMBL4212186)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PDE6C (unknown origin) using FAM-cGMP as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458502(CHEMBL4203481)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458500(CHEMBL4209220)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458496(CHEMBL4214699)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458490(CHEMBL4217166)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458487(CHEMBL4214135)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458482(CHEMBL4208487)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using fluorogenic HDAC subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458491(CHEMBL4202521)
Affinity DataIC50: 7nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using fluorogenic HDAC subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458493(CHEMBL4204952)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458480(CHEMBL4212445)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458479(CHEMBL4212186)
Affinity DataIC50: 11nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458499(CHEMBL4213615)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458486(CHEMBL4210653)
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458479(CHEMBL4212186)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458483(CHEMBL4212866)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458476(CHEMBL4207538)
Affinity DataIC50: 20nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458498(CHEMBL4207409)
Affinity DataIC50: 27nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458495(CHEMBL4209025)
Affinity DataIC50: 31nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458492(CHEMBL4207836)
Affinity DataIC50: 33nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458481(CHEMBL4218554)
Affinity DataIC50: 36nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458491(CHEMBL4202521)
Affinity DataIC50: 37nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 38nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458485(CHEMBL4216635)
Affinity DataIC50: 42nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458484(CHEMBL4216348)
Affinity DataIC50: 47nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458494(CHEMBL4206296)
Affinity DataIC50: 48nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458478(CHEMBL4217821)
Affinity DataIC50: 48nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 51nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458494(CHEMBL4206296)
Affinity DataIC50: 53nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458478(CHEMBL4217821)
Affinity DataIC50: 62nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458502(CHEMBL4203481)
Affinity DataIC50: 66nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458476(CHEMBL4207538)
Affinity DataIC50: 77nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458492(CHEMBL4207836)
Affinity DataIC50: 79nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458488(CHEMBL4204146)
Affinity DataIC50: 87nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458480(CHEMBL4212445)
Affinity DataIC50: 89nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM50458487(CHEMBL4214135)
Affinity DataIC50: 98nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Navarra

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
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