Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50002738
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant GST-tagged human PDE9A2 expressed in insect cells using cGMP as substrate after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE3A (484 to 1141 residues) expressed in Sf9 cells using cAMP as substrate after 60 mins by IM...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant rat PDE10A expressed in Sf9 insect cells using cGMP or cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human PDE11A4 expressed in Sf9 insect cells using [3H]cGMP or [3H]cAMP as substrate after 10 mins by scintillation counting...More data for this Ligand-Target Pair
