Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50001805
TargetRibosomal protein S6 kinase alpha-3(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369721(CHEMBL3702836)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to RPS6KA3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US8476284, 13 | US10894048, Ref. Ex Comp. 1)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BTK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US9987276, Compou...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369720(CHEMBL3979355)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369721(CHEMBL3702836)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM36516(4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morp...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369718(CHEMBL4172284)
Affinity DataIC50: 2nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369722(CHEMBL4175428)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50175583(ACP-196 | Acalabrutinib | US9758524, Example 6 | U...)
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369723(CHEMBL4167139)
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50369720(CHEMBL3979355)
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369722(CHEMBL4175428)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369719(CHEMBL4162057)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US9987276, Compou...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)
Affinity DataIC50: 7nMAssay Description:Inhibition of BTK (unknown origin) assessed as reduction in TNF productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50012060(CHEMBL3263640)
Affinity DataIC50: 8nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US8476284, 13 | US10894048, Ref. Ex Comp. 1)
Affinity DataIC50: 11nMAssay Description:Inhibition of ITK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369720(CHEMBL3979355)
Affinity DataIC50: 11nMAssay Description:Inhibition of ErbB4/HER4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50012060(CHEMBL3263640)
Affinity DataIC50: 14nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50160871(BI 1482694 | HM61713 | Olmutinib)
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR exon 19 deletion and L858R mutant phosphorylation in human NCI-H1975 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369718(CHEMBL4172284)
Affinity DataIC50: 36nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50012060(CHEMBL3263640)
Affinity DataIC50: 36nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSTE20-like serine/threonine-protein kinase(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)
Affinity DataIC50: 43nMAssay Description:Inhibition of SLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369718(CHEMBL4172284)
Affinity DataIC50: 57nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)
Affinity DataIC50: 64nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US8476284, 13 | US10894048, Ref. Ex Comp. 1)
Affinity DataIC50: 78nMAssay Description:Inhibition of TEC (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US8476284, 13 | US10894048, Ref. Ex Comp. 1)
Affinity DataIC50: 200nMAssay Description:Inhibition of LYN (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369724(HM71224 | Ly3337641 | Poseltinib)
Affinity DataIC50: 652nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50160871(BI 1482694 | HM61713 | Olmutinib)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild type EGFR phosphorylation in human H358 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US9987276, Compou...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369723(CHEMBL4167139)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US8476284, 13 | US10894048, Ref. Ex Comp. 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SYK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed