Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50002975
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465350(CHEBI:4715 | Drimenin)
Affinity DataIC50: 970nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465349(Cinnamolide)
Affinity DataIC50: 1.57E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465350(CHEBI:4715 | Drimenin)
Affinity DataIC50: 1.78E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465349(Cinnamolide)
Affinity DataIC50: 2.62E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465349(Cinnamolide)
Affinity DataIC50: 4.64E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465350(CHEBI:4715 | Drimenin)
Affinity DataIC50: 1.38E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50318479((1R,4aS,8aS)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-oc...)
Affinity DataIC50: 4.82E+4nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50318479((1R,4aS,8aS)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-oc...)
Affinity DataIC50: 6.25E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50318479((1R,4aS,8aS)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-oc...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465351(DENDOCARBIN A)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
California Northstate University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50465351(DENDOCARBIN A)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (+/-)-epibatidine-induced calcium influx preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed